John P. Chute, MD
Professor of Medicine
Professor of Pharmacology & Cancer Biology
Levine Science Research Center, 450 Research Drive, Durham, NC 27708
Box 91009, Duke University, Durham, NC 27710
firstname.lastname@example.org | 919-668-2149 (phone) | 919-613-2670 (fax)
Our laboratory studies the mechanisms that regulate hematopoietic stem cell self-renewal and regeneration. In concert with this, we focus particularly on the hematopoietic stem cell niche or microenvironment to define the extrinsic signaling pathways through which the bone marrow microenvironment regulates hematopoietic stem cell self-renewal, differentiation, repair, and reconstitution.
Our research directly focuses on defining specific signaling pathways that regulate stem cell fate but also has substantial implications for the development and application of stem cell therapies for malignant and non malignant diseases.
The Chute Lab is supported by the following sources: